| Protein_S_Deficiency_and_Thrombophilia Information about these rare medical conditions, anticoagulant therapy, research and online forum. |
| Rare_Bleeding_Disorder_Database_(RBDD) A network of the hemophilia centres around the world by International Society of Thrombosis and Haemostasis. |
| UIUC_Hematology_Resource_Page Features diagrams and information about the various thrombophilic genetic markers, general information about clotting, glossary, and list of research sources. |
| Vicky\'s_Website The story of one woman's battle against acquired factor VIII inhibitor. |
| Viewpoint_Online__Coagulation Features articles about blood coagulation disorders including activated protein C resistance, von Willbrand's disease, and hypercoagulability. |
| Egypt_-_National_Institute_of_Occupational_Safety_and_Health_(NIOSH) This government agency is engaged in scientific and applied research, training, advisory field services, and information activities in the field of occupational safety and health. |
| Mauritius_-_Ministry_of_Labour,_Industrial_Relations_&_Employment One of the units of this ministry is the Occupational Safety and Health Inspectorate, responsible for the enforcement of safety and health legislation, and for the provision of information in the fiel |
| South_Africa_-_Department_of_Health_-_National_Centre_for_Occupational_Health_(NCOH) This government centre, based in Johannesburg, is primarily concerned with the prevention of work-related illness in South Africa. |
| Abstracts__Genetics_of_Dystonia Idiopathic torsion dystonia, by Laurie Ozelius, Molecular Neurogenetics Unit, Massachusetts General Hospital, Charlestown, Ma. 2nd Workshop Neurogenetics in Germany, Munich, October 19-21, 1995. |
| ADDER_-_Dystonia_Research Information about the organization which promotes medical and patient education about movement disorders. Includes a newsletter, publications, definitions and links. |
| The_CaF_Directory_-_Dystonia Information about dystonia from the Contact a Family charity, UK. |
| Care4Dystonia Information about dystonia, treatment, toxin use, medical care and alternative therapies. Newsletter. |
| Dopa_Responsive_Dystonia_Central Information and support for people and families afflicted with this disorder, GTP Cyclohydrolase Deficiency and Segawa's Dystonia. |
| The_Dystonia_Society_(UK) UK charity providing information and support for people with dystonia. |
| Dystonias Information page compiled by NINDS, the National Institute of Neurological Disorders and Stroke. |
| The_Family_Village_-_Dystonia Information, contacts, chat rooms, links related to dystonia. |
| IPL_Ready_Reference_Collection_-__Dystonia Dystonia reference. |
| Living_with_Dystonia_from_Childhood_to_hood Information about dystonia, including personal information and links to dystonia organizations. |
| Medicine_Net A description of dystonia musculorum deformans. |
| Movement_Diseases_and_Disorders__Dystonia An article explaining what dystonia musculorum deformans is, the symptoms, causes and treatment. From UCLA Neurosurgery. |
| Paroxysmal_Choreoathetosis_Disease Information compiled by the National Institute of Neurological Disorders and Stroke (NINDS). Condition, symptoms, treatment, and prognosis. |
| Spasmodic_Dysphonia_-_Patient_Information Information about the voice disorder spasmodic dysphonia. Includes a listing and review of other sites. |
| AFP_&_Triple_Screen_Testing Testing information. |
| CDC__Prenatal_Discussion_of_HIV_Testing Testing for the HIV virus during pregnancy. |
| fFN_Test Offers information about premature labor and using the fetal fibronection test to assess the risk of premature delivery. |
| How_Stuff_Works Illustrated narrative describing an assortment of testing decisions. |
| Mother_and_Child Discusses purpose and procedure of chorionic villus sampling. Includes list of advantages and disadvantages compared to amniocentesis. |
| NT_Laboratories Offers information on a variety of prenatal tests, including amniocentisis, and the ultra-screen. |
| Perinatology_com Reference for the clinical geneticist. |
| Picture_Perfect___The_Politics_of_Prenatal_Testing Article by Elizabeth Kristol, addressing the safety and necessity of screening. |
| Prenatal_Testing Definitions of the following testing procedures: amnioscentesis, ultrasound, chorionic villi sampling, and fetal development. |
| Ultrasound_of_Fetal_Biometrics_and_Growth Details of basic measurements including scan pictures and diagrams. |
| University_of_Pennsylvania Information regarding chorionic villi sampling. |
| AAAAI__Some_Foods_May_Cause_Reactions_in_Latex_Sensitive_Individuals Foods containing proteins similar to latex that may trigger allergic reactions, including anaphylaxis. |
| American_Latex_Allergy_Association Provides resources for people allergic to natural rubber latex, including latex free alternative product lists, informational packets, support groups, and a newsletter. |
| Health_Link_MCW An article about healthcare workers and latex allergies. Includes diagnosing and treatment. |
| Latex_Allergy A guide to creating a latex-free environment with a photo database of relevant products. How to recognize Intra-operative anaphylaxis and how to receive a sensitized patient. |
| Latex_Allergy Latex Allergy article written by Dr. Sumana Reddy (1998). Covers basic facts about natural rubber latex allergy. |
| Latex_Allergy An explanation as to what latex is and about the allergy. Reactions, who is at risk, the connection between latex and food and what to do if you think you have this allergy. |
| Latex_Allergy_Links_Message_Board A semi-public message board for posting information, asking questions, or responding to questions regarding latex allergy issues. |
Welcome
to FactorVIIa.com, The Factor VIIa Information Source, an Internet
site designed for physicians and other health care personnel who want
information about topics related to the pathophysiology, pharmacology,
and clinical aspects of bleeding, coagulation, and hemostasis, including
information about recombinant coagulation Factor VIIa (NovoSeven®),
a novel therapeutic approach to manage bleeding.
Hemostasis is defined as the stoppage of bleeding or hemorrhage;
or the stoppage of blood flow through a blood vessel or body part.
In fact, hemostasis is a complex control system through which blood
is kept from leaking outside blood vessels. One of its main components
is a complex coagulation cascade involving numerous blood clotting
proteins or factors, platelets and tissue factor. Tissue factor
is a lipoprotein that is constitutively present on the membrane
of certain cells. When it is exposed, it binds to Factor VII (one
of the central coagulation factors) and activates the tissue factor
dependent coagulation pathway. Factor VIIa plays a pivotal role
in hemostasis.
Clinical
applications of hemostatic agents are rapidly growing in clinical
medicine. Because of the pivotal role of hemostasis in surgery,
critical care, trauma, perioperative medicine, and hematology, therapeutic
approaches to treating bleeding and bleeding problems are important.
Further, a broad spectrum of thrombin and platelet inhibitors have
assumed a pivotal role in clinical medicine, and many of these agents
are not readily reversible. Novel therapeutic approaches are important
to consider when managing patients with potential for severe life
threatening bleeding. This site will explore important issues in
managing these patients and understanding the clinical problems
they pose.
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