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Top Headlines — The Cancer Letter Skip to content. | Skip to navigation Site Map Accessibility Contact Search Site Advanced Search… The Cancer Letter Sections Home Publications About Us Advertising The Cancer Letter Archive The Clinical Cancer Letter Archive BRR Archive TCL In The News FAQ Personal tools Log in Youare here: Home Navigation Home Publications About Us Advertising The Cancer Letter Archive The Clinical Cancer Letter Archive BRR Archive TCL In The News FAQ Contact Us Subscribe or renew subscription Google Ad Links Document Actions   Top Headlines by Kirsten Goldberg — last modified 2008-09-11 10:29 Research vs. Delivery? Advisors Debate NCI Role In Review of Community Program From The Cancer Letter, Nov. 21, 2008: The NCI Board of Scientific Advisors was forced to confront a fundamental question as it reviewed the institute’s pilot project slated to provide $15 million for community hospitals:Should the institute focus exclusively on research, or should it be spending its dwindling resources on improving the delivery of cancer care to rural and underserved populations?“That is not research; it’s quality improvement,” BSA member Jane Weeks, chief of the Division of Population Sciences at Dana-Farber Cancer Institute, said of the signature project of Institute Director John Niederhuber at a board meeting Nov. 6.The board was never asked to vote yea or nay on the NCI Community Cancer Centers Program. However, at its most recent meeting, BSA heard a status update on the year-old program that gives$500,000 a year for three years to each of the 10 community hospitals selected to take part.“If you took $500,000 and pumped it into any center in the U.S., my God, I would hope the quality ofcare would get better,” said Weeks. “But that is not a sustainable model.”For the full story, click on The Cancer Letter Archive at left to download the Nov. 21 issue (subscription or day pass required). _____ tags: NCI| clinical trials Friday, November 21, 2008 in NCI | Permalink | Comments (0)      Vermont Cancer Center Loses NCI Designation From The Cancer Letter, Nov. 14, 2008: Nov. 30 will be the last day for the Vermont Cancer Center to ask NCI to renew its designation as a comprehensive cancer center. The center will let that deadline pass.Filing an application would have been futile, said Bernard Levin, a cancer prevention expert who came to the center as a consultant and agreed to serve as interim director for a few months.“I had to deliver a tough message,” said Levin, former vice president for cancer prevention and population sciences at M.D. Anderson Cancer Center. “I came there to tell the faculty and administration that this is not going to work. They didn’t need to spend time, money, and effort to try and submit a renewal they would have been ashamed of.”The center’s infrastructure—particularly its clinical and translational research programs—no longer merits the prestigious designation it held for three decades, Levin said.It’s not as though a tsunami gathered suddenly in the frigid waters of Lake Champlain to overwhelm the Burlington-based cancer center. The “matrix” center, affiliated with the University of Vermont and the non-profit Fletcher Allen Health Care, was warned repeatedly about the lack of institutional commitment, the lack of authority of the center director, and problems in the clinical research programs.For the full story, click on The Cancer Letter Archive at left to download the Nov. 14 issue (subscription or day pass required). _____ tags: NCI Friday, November 14, 2008 in NCI | Permalink | Comments (0) Obama Plan Would Double Cancer Funding, Increase Trial Enrollment From The Cancer Letter, Nov. 7, 2008: The Obama campaign laid out a clear plan for combating cancer, and now the question is how closely President Obama would follow the plan.The Obama cancer plan calls for doubling federal expenditure on cancer research over the next five years, increasing accrual to clinical trials to 10 percent of all cancer patients, reinstating the requirement that Medicare pay for routine care costs associated with clinical trials, and instituting public health measures that include colorectal cancer screening and smoking cessation.For the full story, click on The Cancer Letter Archive at left to download the Nov. 7 issue (subscription required).Another story in this week's issue reports that several cancer groups, pharmaceutical companies, and NCI are lobbying FDA to spell out how data collection procedures and evidence requirements have changed as a result of the agency’s decision to approve drugs based on their ability to delay cancer progression.In the process of approving recent applications, the agency has asked for a variety of changes in the methods clinical trialists use to collect data. Demanding these changes, the agency argued that unlike survival, the old, unambiguous metric that used to be the gold standard for drug approval, time to progression is subject to bias and therefore requires different methodology. _____ tags: Congress| FDA| NCI| White House Friday, November 07, 2008 in FDA | NCI | research funding | Permalink | Comments (0) Randomized Trial Finds Supplement Use Didn't Prevent Prostate Cancer From The Cancer Letter, Oct. 31, 2008: The Southwest Oncology Group is telling more than 35,000 men participating in a large prostate cancer prevention trial to stop taking the dietary supplements selenium and vitamin E, because no benefit for their use has been shown after a median follow-up of five and a half years.The independent Data and Safety Monitoring Committee for the trial met on Sept. 15 to review study data and found that selenium and vitamin E, taken alone or together for an average of five years, did not prevent prostate cancer. The committee also calculated that it was unlikely the supplements would ever produce a 25 percent reduction in prostate cancer, as the studywas designed to show.For the full story, click on The Cancer Letter Archive at left to download the Oct. 31 issue (subscription required). _____ tags: NCI| cancer prevention Friday, October 31, 2008 in NCI | cancer prevention | Permalink | Comments (0) McCain Surgery Puzzles Melanoma Experts, But Some Clues Found In Reporters’ Notes From The Cancer Letter, Oct. 24, 2008:  A massive scar that begins on John McCain’s left temple, bisects his cheek and runs down his neck is a graphic reminder of a melanoma surgery he had eight years ago.Experts in treating the deadly cancer say this scar is difficult to explain. In August 2000, when the Arizona Senator received his surgery at the Mayo Clinic in Scottsdale, he possibly could have been spared the disfigurement had he gone to a major academic center with a strong melanoma program.Could the scar be interpreted as indication that the 72-year-old Republican Presidential candidate had more advanced disease than the campaign acknowledged? Could it be that he received “VIP care” that bypasses normal procedures, but sometimes ends up producing worse outcomes for John McCain than for Joe the Plumber?Download the full story for no charge here. _____ tags: Congress| news makers Friday, October 24, 2008 in cancer treatment | news makers | Permalink | Comments (0) Cooperative Groups List High Priority Trials In Breast Cancer From The Cancer Letter, Oct. 17, 2008: A panel of breast cancer experts convened by the Coalition of Cancer Cooperative Groups has identified 13 breast cancer clinical trials that it said should receive the highest priority for patient enrollment.The coalition’s Scientific Leadership Council in Breast Cancer said the phase III trials it selected from more than 515 ongoing trials have the greatest potential to improve treatment and survival. The group urged physicians to discuss these trials with eligible patients. The coalition also said it hoped that patient advocacy groups and health insurers would help promote the trials and facilitate patient enrollment.An executive summary of the report and fact sheets on the trials will be posted on the coalition’s website in the near future. For the full story, click on The Cancer Letter Archive at left to download the Oct. 17 issue (subscription required). _____ tags: clinical trials Friday, October 17, 2008 in cancer treatment | Permalink | Comments (0) Colon Cancer Screening Guideline Triggers Debate From The Cancer Letter, Oct. 10, 2008: The U.S. Preventive Services Task Force earlier this week published a guideline on screening for colorectal cancer. The guideline is fundamentally different from the consensus guideline put out jointly by the American Cancer Society, the American College of Radiology, and three gastroenterology societies.The ACS guideline, published in March, discusses the pros and cons of screening methods that have an over-50 percent chance of detecting polyps and colon cancer. In contrast, the Preventative Services guideline, released Oct. 6, was intended to be a rigorous analysis of impact of several programs of repeated screening.The two competing guidelines raise questions about what a screening guideline should look like. Should guideline-writing be a pragmatic and, if necessary, political process aimed at increasing screening? Or should it be a pure, intellectual exercise that excludes vested interests, follows a pre-specified plan, considers screening strategies (as opposed to modalities), and rigorously weighs health benefits against potential harm before making a recommendation?For the full story, click on The Cancer Letter Archive at left to download the Oct. 10 issue (subscription required). _____ tags: cancer screening Friday, October 10, 2008 in cancer screening | Permalink | Comments (0) Amgen Announces Cochrane Findings: ESAs Increase Risk Of On-Study Death From The Cancer Letter, Oct. 3, 2008: Something was missing from a press release announcing the Cochrane Collaboration’s preliminary result from a pooled analysis of ESA studies.That something was comment from the investigators who conducted the patient-level meta-analysis.The only quote belonged to Roger Perlmutter, executive vice president for Research and Development at Amgen Inc., one of the three companies that provided the randomized trial data for the pooled analysis.It was, in fact, Amgen that issued the press release about the Cochrane findings.For the full story, click on The Cancer Letter Archive at left to download the Oct. 3 issue (subscription required). _____ tags: FDA Friday, October 03, 2008 in FDA | cancer treatment | Permalink | Comments (0) ACS Chief Medical Officer Calls For Audit of I-ELCAP Data From The Cancer Letter, Sept. 26, 2008: The top physician of the American Cancer Society said an audit of a lung cancer screening study by the International Early Lung Cancer Action Program would be required if its results are to be taken seriously.“I am very concerned about the I-ELCAP data and the I-ELCAP findings, and I can’t justify using I-ELCAP at this time,” ACS Medical Director Otis Brawley said at a meeting he called to consider pooling data from lung cancer prevention studies. “I think we can only use the I-ELCAP data if there is an external audit to verify that data, and there is an independent reanalysis of that data.”For the full story, click on The Cancer Letter Archive at left to download the Sept. 26 issue (subscription required). _____ tags: cancer screening Friday, September 26, 2008 in cancer screening | Permalink | Comments (0) Fundraiser Poses Eight Questions For Stand Up To Cancer From The Cancer Letter, Sept. 19, 2008: In a commentary, professional fundraising consultant Harry Freedman asks Stand Up To Cancer to provide to the public additional information about its Sept. 5 telethon:The Cancer Letter and The Chronicle of Philanthropy have attempted to get answers to some very important questions about this event, but the answers, alas, were not informative, and, in my opinion, disingenuous and evasive. How can the organizers claim to be unaware of how much money they spent and how much they brought in? Jerry Lewis, at the end of his telethon, announces exactly how much was raised, and within a few days, the net proceeds are reported to the public. The same holds true for St. Jude’s Children’s Research Hospital and many other high-profile fundraisers. The answer we have seen so far—that SU2C has raised “more than” $100 million—isn’t good enough. I hope that cancer advocacy groups will demand that the SU2C organizers make a full accounting of the costs, the revenues and the plans for distributing the net funds raised through the Sept. 5 event. For the full story, click on The Cancer Letter Archive at left to download the Sept. 19 issue (subscription required). _____ tags: research funding Friday, September 19, 2008 in research funding | Permalink | Comments (0) Cancer Telethon Attracts Small Audience, Generates Expectations—And Questions From The Cancer Letter, Sept. 12, 2008: Early in the broadcast of a nationally televised program raising money for cancer research the actress and breast cancer survivor Fran Drescher pointed into the distance, toward a balcony at the Kodak Theatre in Los Angeles.“Please join me in welcoming 75 advocacy organizations—including my own, Cancer-Schmancer—representing all cancer types,” she said. “They are here to prove that together we can change the way cancer is researched in this country.”Thus, the organizers of the show biz benefit aimed to raise money for cutting-edge translational research acknowledged the folks who have the expertise and moral authority to judge the usefulness of the event broadcast by the networks between 8 and 9 p.m. on Sept. 5.Stand Up To Cancer, or SU2C, generated a massive wave of media coverage and reportedly raised more than $100 million. When the event was first announced last May, organizers said informally that they were hoping for $250 million.Click on The Cancer Letter Archive at left to download the Sept. 12 issue (subscription required). _____ tags: research funding Friday, September 12, 2008 in research funding | Permalink | Comments (0) Cancer Groups Object To NIH Grant Coding; Amgen Changes Contract Again Two top stories this week from The Cancer Letter, Sept. 5, 2008: NIH Grant Coding Under Fire From Cancer Patient GroupsCongress recently told NIH to develop a coding system to keep track of spending on research on specific diseases.NIH carried out the orders contained in the 2006 reauthorization bill, but has triggered objections from NCI officials and cancer patient advocacy groups, who contend that the coding system provides inaccurate and misleading estimates of funding allocated to various categories of cancer research.The system uses word recognition software to search through the NIH grant portfolio and determine the categories applicable to every grant. If a grant covers multiple topics, its dollars will be counted 100 percent toward all of the categories. Thus, the total will add up to greater than the NIH budget.Amgen Replaces “Bundling” Contract With Three Separate Contracts For Growth Factors Amgen Inc. has relaxed its system of incentives for marketing red and white blood cell growth factors.The new schema, scheduled to go in effect Oct. 1, abandons the interlocking incentives the company used to induce oncologists to meet aggressive sales targets for supportive care agents for treating anemia and neutropenia.Click on The Cancer Letter Archive at left to download the Sept. 5 issue (subscription required). _____ tags: Congress| NCI| research funding Friday, September 05, 2008 in NCI | oncology profession | research funding | Permalink | Comments (0) Next 12 items » [1] 2 3 4 ... 7 Log in Login Name Password Cookies are not enabled. You must enable cookies before you can log in.  Forgot your password? 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